Document accompanying psychoactive substances
Product name Rubifen (RUBIFEN 10 mg)
component
In 1 tablet contains important medicines. Methylphenidate HCI 10 mg
Product characteristics
Flat, white pills with a line in half on one side and the letters “RU” and the number “10” on the other side, smooth.
Pharmacological properties
Pharmacodynamics: methylphenidate It is a substance that stimulates the central nervous system. Mechanism of action in treatment Not yet known for sure
A stimulating effect on the central nervous system may be due to an increase in levels. norepinephrine and dopamine in synaps
which is the result of increasing the secretion of substances transmitted through the nervous system extraneuronal space inhibits presynaptic reuptake
Neurons in the brainstem, arousal system and cortes
Pharmacodynamics: methylphenidate It is a substance that stimulates the central nervous system. Mechanism of action in treatment Not yet known for sure
A stimulating effect on the central nervous system may be due to an increase in levels. norepinephrine and dopamine in synaps
which is the result of increasing the secretion of substances transmitted through the nervous system extraneuronal space inhibits presynaptic reuptake
Neurons in the brainstem, arousal system and cortes
Pharmacokinetics: The drug is rapidly absorbed from the gastrointestinal tract. and binds to plasma proteins approximately 10-30 percent. Drug concentration levels
in the blood is highest after taking the drug approximately 2 hours. It is metabolized by the de-esterification process.
ritalinic acid, which has very little pharmacological activity, has a half-life of 2.4 hours in children and 2.1 hours in adults.
Excreted in the urine approximately 78-97% within 48 – 96 hours in the form of metabolites and excreted in the feces approximately 1-3%.
in the blood is highest after taking the drug approximately 2 hours. It is metabolized by the de-esterification process.
ritalinic acid, which has very little pharmacological activity, has a half-life of 2.4 hours in children and 2.1 hours in adults.
Excreted in the urine approximately 78-97% within 48 – 96 hours in the form of metabolites and excreted in the feces approximately 1-3%.
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