Tradolgesic 50 mg 🇹🇭

**Relief of moderate to moderately severe pain

**Acts as a dual-action analgesic: μ-opioid receptor agonist and reuptake inhibitor of serotonin and norepinephrine

**May cause sedation, dizziness, and dependency

**Should not be combined with CNS depressants

**Contraindicated in patients with seizure history

**Avoid during pregnancy, especially in the third trimester

**Tramadol was first developed in the 1960s by Grünenthal GmbH, a German pharmaceutical company. It was launched in 1977 in West Germany and later worldwide.

**Tradolgesic® is a locally marketed brand in Thailand by Bangkok Drug, used under regulated clinical guidance.

**Exact launch year for Tradolgesic is unclear, but its availability in Thailand suggests long-standing clinical use (likely >10 years).

**Recreational use, including combination with cough syrup or alcohol (“Lean” / “Purple Drank”)

**Crushing and injecting the substance (extremely dangerous)

**Overdose risks: respiratory depression, seizures, coma, and death

**Tramadol is classified as a Schedule II/IV drug depending on jurisdiction

**Adverse effects: nausea, vomiting, dry mouth, diaphoresis, mood changes

**Some studies suggest increased risk of suicidal ideation with long-term use